2,291 research outputs found
¿Por qué es importante establecer una rúbrica de evaluación? El caso del curso Clínica de Exodoncia y Cirugía
En la actualidad los procesos evaluativos han cobrado importancia, pues se requieren instrumentos objetivos que ofrezcan un medio para valorar las competencias logradas por el estudiantado, en determinado proceso de enseñanza-aprendizaje. Las rúbricas de evaluación ofrecen un mecanismo objetivo, que estandariza los indicadores a valorar, según el rendimiento mostrado por el estudiantado. Además, le permite al personal docente orientar y retroalimentar al alumnado, quienes también podrán utilizar el instrumento para autoevaluarse y prepararse de antemano, de acuerdo con las especificaciones descritas en la rúbrica. El objetivo del presente trabajo es elaborar una rúbrica de evaluación para el curso de Clínica de Exodoncia y Cirugía. Dicho instrumento se realizó considerando las opiniones del 40% del profesorado a cargo del curso, por medio de una entrevista semi-estructurada. Esta rúbrica ofrece una herramienta que estandariza el proceso de evaluación de las "presentaciones de caso" y permite que el equipo docente pueda retroalimentar al estudiantado y favorece la interacción docente-estudiante
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The Relationship Between Subtle Sexism and Women\u27s Careers Explained by Cognitive Processes and Moderated by Attachment Styles
The present study investigated how experiences of subtle sexism related to women’s career outcomes. Prior research has focused on attitudes and impacts of subtle sexism, whereas this study focused on personal experiences of subtle sexism. Due to its normative nature, subtle sexism occurs often and can be difficult to classify as sexism. The study found that participants who encountered more subtle sexism reported lower levels of advancement perceptions and work engagement was indirectly impacted by subtle sexism. Interestingly, although it was expected that rumination would cause cognitive overload, participants in this study exhibited resilience which indirectly impacted their advancement perceptions. Overall, the findings build on prior research and amplify the need for the denunciation of subtle sexism
Putting the pieces together : elucidation of podocyte biology in the homeostasis of the kidney filtration barrier
End-stage renal disease (ESRD) is a devastating condition that can only be treated
with chronic dialysis or kidney transplantation. ESRD treatment costs account for up to
10% of healthcare budgets in the Western world. The 5-year survival for patients in
dialysis is only about 40%. Glomerular disease processes are the main cause of ESRD.
Despite this, our basic knowledge on the biology and disease processes of the
glomerulus is poor. As a result, we still lack effective therapy options to stop the
progression of glomerular diseases.
In this thesis we have identified a number of candidate genes and proteins that
could have an essential role in the glomerular homeostasis. In the first project, we
identified a group of neural proteins, Hip1, Nfasc and Olfml2, which are enriched in
podocytes. We used these markers to provide further evidence that podocytes are
present in glomerular crescent lesions that occur in inflammatory diseases of the
glomerulus.
In project 2, we studied the functional role of another neural protein, dendrin, in
the kidney by generating and characterizing a knockout (KO) mouse line. Previously,
we and others have shown that dendrin is very specific to podocytes and interacts with
cd2ap and nephrin, two podocyte proteins imperative for the maintenance of the kidney
barrier. The KO mouse model showed that dendrin is not needed for the development
or maintenance of the glomerulus filtration barrier. Furthermore, the outcome of
glomerular disease in two injury models was unaffected by the absence of dendrin. This
suggests that dendrin does not have a role in the development of glomerular damage in
these two models.
In project 3, we identified Tmem234, Slfn5, Lrrc49 and Znf185 as highly
podocyte-enriched molecules. Morpholino knockdown experiments in zebrafish
showed that the silencing of Tmem234 results in podocyte foot effacement and
proteinuria in pronephros. Thus, Tmem234 seems to have an important role in the
formation of functional filtration barrier in zebrafish pronephros, and therefore it is
reasonable to speculate that it can have also an important role in the mammalian kidney.
Lastly, in project 4 we identified a mediator protein subunit, Med22, to be
essential for the kidney filtration barrier. In zebrafish pronephros, Med22 morphants
exhibit defective capillary loop formation and leak large proteins to tubuli. In mice, full
KO mice die during embryonic development. In podocyte-specific KO animals kidney
development proceeds normally. However, these mice exhibit proteinuria starting from
8 weeks of age that progresses to ESRD by 16 weeks of age. Histological analysis
shows the accumulation of caveolin-positive vesicles in the cytoplasm of podocytes. As
these vesicles became larger, we detected the loss of podocytes that leads to
glomerulosclerosis and ESRD. Thus, Med22 seems to regulate vesicular trafficking in
podocytes and be essential for podocyte survival.
This thesis provides novel insights into podocyte biology and obviously opens up
new possibilities to study these candidate genes in glomerular function and pathology
Hydrogen trapping in an API 5L X60 steel
Electrochemical hydrogen permeation tests were performed on an API 5L X60 steel to study trapping and diffusion properties in the as-received (AR) and in a cold-rolled (CR) state, at 30, 50 and 70 C. Hydrogen trapping was characterized by assuming saturable traps in local equilibrium. Binding energies (DG) and trap densities (N) were determined by fitting a trapping theoretical model to experimental data. Both conditions AR and CR present a high density of weak traps |DG| < 35 kJ/mol, namely N = 1.4 105 and 7.9 104 mol/cm3 respectively. Strong trapping sites were detected (72 < DG < 57 kJ/mol) and their densities increased markedly after cold-rolling.Fil: Castaño Rivera, Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de San Martín. Instituto Sabato; ArgentinaFil: Ramunni, Viviana Patricia. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bruzzoni, Pablo. Comisión Nacional de Energía Atómica. Gerencia del Área de Energía Nuclear. Unidad de Actividad de Materiales (CAC); Argentin
Detección de problemas de aprendizaje
Documento PDF, 119 páginasGuía de estudio para el curso Detección de problemas de aprendizaje, código 0715, que imparte la Escuela de Ciencias Sociales de la UNED.Universidad Estatal a Distancia de Costa Ric
El feminismo aristocrático: violencia simbólica y ruptura soterrada a comienzos del siglo XX
Desde su producción misma, todo producto cultural, simbólico, está en relación directa y recíproca con la sociedad en la que nace. Es mediatizado por las condiciones que ésta impone (políticas, económicas, etc), a la vez que, al producir significaciones nuevas, incide en las constantes transformaciones del entorno. Desde esta óptica —la de Bajtin—,[1] la literatura debe ser considerada, pues, como una práctica social que reproduce en su estructura la ideología dominante en cierto lugar y cierto momento histórico; esto es, que asume su referencialidad como un rasgo interno. Aceptando estas premisas, podemos encontrar en la literatura una herramienta que si bien no es de por sí suficiente, sí nos puede resultar útil o complementaria al momento de tomarle el pulso a una sociedad
On the Influence of Shade in Improving Thermal Comfort in Courtyards
This study analyzes the thermal performance of courtyards in traditional buildings in the
city center of Córdoba (South of Spain), one of them displaying a shading component, to determine
the influence of this precise element. The courtyards have been monitored simultaneously during a
summer period when temperatures during the day reached over 45 °C. The obtained data was
contrasted, and we confirmed that the shading element provided an improvement of the thermal
performance of the courtyard which doubled the thermal leap between outdoor and inside the
courtyard temperatures when the shading element was installed, in comparison to the courtyard
without shade. Therefore, the tempering effect of courtyards can be significantly improved by
means of using these simple elements
Santa Teresa: ciudad-moridero en 2666
In the novel 2666, Roberto Bolano configures Santa Teresa city (transcript of Ciudad Juarez) in two levels. The first real, based on police chronicles, and the second one, clearly imaginary, where the characters, most of them related to literature, crash with a grotesque reality, configured by the crimes that take place in the city. Santa Teresa is the last city of Latin America, and also a kind of cemetery for the continent.En la novela 2666, Roberto Bolano configura Santa Teresa (trasunto de Ciudad Juarez) en dos niveles. Uno real, basado en la cronica policial, y otro netamente literario, donde personajes ficticios, en su mayoria personajes que de una u otra manera se dedican a la escritura, tropiezan a golpes con una realidad grotesca, tamizada por los crimenes que se desarrollan en la ciudad. Santa Teresa es la ciudad final de Latinoamerica y a la vez una especie de cementerio del continente
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